About The Lab

The Lab of Neuroendocrinology, led by Professor Randall R. Sakai, Ph.D., examines the role of the renin-angiotensin system and adrenal steroids in mediating thirst and sodium appetite. These studies provide animal models in which to study innate motivated behaviors as they are related to conditions such as dehydration, hypertension and adrenal insufficiency.

Another area of his research investigates the behavioral, neuroendocrine, and neurochemical effects associated with chronic stress. Understanding the mechanisms underlying the regulation of the stress response as well as the long-term consequences of stress may enhance rational clinical therapies for treatment of affective disorders such as depression and post-traumatic stress disorder. Both programs of research utilizes an interdisciplinary approach to examine behavioral and physiological phenomena at multiple levels and includes behavioral observations, in vivo manipulations such as antisense oligodeoxynucleotide technology, and molecular biological assays.

Location
We are now currently located at the Genome Research Institute (a.k.a. the G.R.I.) at 2170 East Galbraith Road. If you have any questions, please visit our Contact Us page to obtain our contact information.

Want More?
If you want to learn more about our lab and the people that make it happen, all you have to do is simply click on the links above to the left to navigate through our web site.

Enjoy!